BREAST TISSUE IN BENIGN TUMOR OF ANAL MARGIN
Keywords:
Adenoma, Anus Neoplasms, Genital Neoplasms, Mammary GlandsAbstract
Abstract:
Background: Adenomas in the anogenital region are uncommon and the origin of this kind of lesion has created confusion. In the past these lesions have been considered as ectopic breast tissues or as cutaneous apocrine glands. More recently they have been defined as mammary-type anogenital glands.
Methods: This case reports an anogenital mass in a 47-year-old woman that was removed and subsequently studied through a pathological and immunostaining study.
Results: Microscopic tissue sections showed a morphologic pattern similar to that of a mammary fibroadenomas, and immunostaining demonstrated the presence of oestrogen receptors and progesterone receptors. The definitive diagnosis was an apocrine adenoma tubulo-papillary without signs of malignancy.
Conclusion: When a tumour of the anal margin of unknown origin is found, it is opportune to consider, although very rare, the adenomas that mimic the mammary tissuesDownloads
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References
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2. Groscurth P. Anatomy of sweat glands. Curr Probl Dermatol. 2002;30:1–9.
3. Woodworth H, Dockerty MB, Wilson RB, Pratt JH. Papillary hidradenoma of the vulva: a clinicopathologic study of 69 cases. Am J Obstet Gynecol. 1971 Jun 15;110(4):501–8.
4. Baisre A, Heller DS, Lee J, Zheng P. Fibroadenoma of the vulva. A report of two cases. J Reprod Med. 2002 Nov;47(11):949–51.
5. Chung-Park M, Zheng Liu C, Giampoli EJ, Emery JD, Shalodi A. Mucinous adenocarcinoma of ectopic breast tissue of the vulva. Arch Pathol Lab Med. 2002 Oct;126(10):1216–8.
6. Irvin WP, Cathro HP, Grosh WW, Rice LW, Andersen WA. Primary breast carcinoma of the vulva: a case report and literature review. Gynecol Oncol. 1999 Apr;73(1):155–9.
7. Piura B, Gemer O, Rabinovich A, Yanai-Inbar I. Primary breast carcinoma of the vulva: case report and review of literature. Eur J Gynaecol Oncol. 2002;23(1):21–4.
8. Yin C, Chapman J, Tawfik O. Invasive mucinous (colloid) adenocarcinoma of ectopic breast tissue in the vulva: a case report. Breast J. 2003 Apr;9(2):113–5.
9. Assor D, Davis JB. Multiple apocrine fibroadenomas of the anal skin. Am J Clin Pathol. 1977 Sep;68(3):397–9.
10. Amalinei C, Giusca SE, Caruntu ID. Fibroadenomas of anogenital mammary-like glands: from embryogenesis anomaly to apocrine origin. Pol J Pathol Off J Pol Soc Pathol. 2015 Sep;66(3):219–23.
11. Konstantinova AM, Shelekhova KV. [Fibroepithelial tumors of the anogenital mammary-like glands]. Arkh Patol. 2017;79(4):40–7.
12. Plantier F, groupe de dermatopathologie de la Société française de dermatologie. [Hidradenoma papilliferum or anogenital mammary-like gland adenoma]. Ann Dermatol Venereol. 2015 Oct;142(10):609–12.
13. Khalsa A, Conway A, Ali L, Heaney S, Helm K. Apocrine Fibroadenoma on the Face: Case Report and Review of the Literature. Am J Dermatopathol. 2016 Mar;38(3):236–8.
14. Kazakov DV, Spagnolo DV, Kacerovska D, Michal M. Lesions of anogenital mammary-like glands: an update. Adv Anat Pathol. 2011 Jan;18(1):1–28.
15. Choi WWL, Tadros TS, Majmudar B. Anal fibroadenoma: report of a common tumor type in an unusual location. South Med J. 2007 Sep;100(9):914–5.
16. van der Putte SC. Mammary-like glands of the vulva and their disorders. Int J Gynecol Pathol Off J Int Soc Gynecol Pathol. 1994 Apr;13(2):150–60.
17. Higgins CM, Strutton GM. Papillary apocrine fibroadenoma of the vulva. J Cutan Pathol. 1997 Apr;24(4):256–60.
18. Konstantinova AM, Spagnolo DV, Stewart CJR, Kacerovska D, Shelekhova KV, Plaza JA, et al. Spectrum of Changes in Anogenital Mammary-like Glands in Primary Extramammary (Anogenital) Paget Disease and Their Possible Role in the Pathogenesis of the Disease. Am J Surg Pathol. 2017 Aug;41(8):1053–8.
19. Castro CY, Deavers M. Ductal carcinoma in-situ arising in mammary-like glands of the vulva. Int J Gynecol Pathol Off J Int Soc Gynecol Pathol. 2001 Jul;20(3):277–83.
20. Pelosi G, Martignoni G, Bonetti F. Intraductal carcinoma of mammary-type apocrine epithelium arising within a papillary hydradenoma of the vulva. Report of a case and review of the literature. Arch Pathol Lab Med. 1991 Dec;115(12):1249–54.
21. Obaidat NA, Awamleh AA, Ghazarian DM. Adenocarcinoma in situ arising in a tubulopapillary apocrine hidradenoma of the peri-anal region. Eur J Dermatol EJD. 2006 Oct;16(5):576–8.
22. Kazakov DV, Belousova IE, Sima R, Michal M. Mammary type tubulolobular carcinoma of the anogenital area: report of a case of a unique tumor presumably originating in anogenital mammarylike glands. Am J Surg Pathol. 2006 Sep;30(9):1193–6.
2. Groscurth P. Anatomy of sweat glands. Curr Probl Dermatol. 2002;30:1–9.
3. Woodworth H, Dockerty MB, Wilson RB, Pratt JH. Papillary hidradenoma of the vulva: a clinicopathologic study of 69 cases. Am J Obstet Gynecol. 1971 Jun 15;110(4):501–8.
4. Baisre A, Heller DS, Lee J, Zheng P. Fibroadenoma of the vulva. A report of two cases. J Reprod Med. 2002 Nov;47(11):949–51.
5. Chung-Park M, Zheng Liu C, Giampoli EJ, Emery JD, Shalodi A. Mucinous adenocarcinoma of ectopic breast tissue of the vulva. Arch Pathol Lab Med. 2002 Oct;126(10):1216–8.
6. Irvin WP, Cathro HP, Grosh WW, Rice LW, Andersen WA. Primary breast carcinoma of the vulva: a case report and literature review. Gynecol Oncol. 1999 Apr;73(1):155–9.
7. Piura B, Gemer O, Rabinovich A, Yanai-Inbar I. Primary breast carcinoma of the vulva: case report and review of literature. Eur J Gynaecol Oncol. 2002;23(1):21–4.
8. Yin C, Chapman J, Tawfik O. Invasive mucinous (colloid) adenocarcinoma of ectopic breast tissue in the vulva: a case report. Breast J. 2003 Apr;9(2):113–5.
9. Assor D, Davis JB. Multiple apocrine fibroadenomas of the anal skin. Am J Clin Pathol. 1977 Sep;68(3):397–9.
10. Amalinei C, Giusca SE, Caruntu ID. Fibroadenomas of anogenital mammary-like glands: from embryogenesis anomaly to apocrine origin. Pol J Pathol Off J Pol Soc Pathol. 2015 Sep;66(3):219–23.
11. Konstantinova AM, Shelekhova KV. [Fibroepithelial tumors of the anogenital mammary-like glands]. Arkh Patol. 2017;79(4):40–7.
12. Plantier F, groupe de dermatopathologie de la Société française de dermatologie. [Hidradenoma papilliferum or anogenital mammary-like gland adenoma]. Ann Dermatol Venereol. 2015 Oct;142(10):609–12.
13. Khalsa A, Conway A, Ali L, Heaney S, Helm K. Apocrine Fibroadenoma on the Face: Case Report and Review of the Literature. Am J Dermatopathol. 2016 Mar;38(3):236–8.
14. Kazakov DV, Spagnolo DV, Kacerovska D, Michal M. Lesions of anogenital mammary-like glands: an update. Adv Anat Pathol. 2011 Jan;18(1):1–28.
15. Choi WWL, Tadros TS, Majmudar B. Anal fibroadenoma: report of a common tumor type in an unusual location. South Med J. 2007 Sep;100(9):914–5.
16. van der Putte SC. Mammary-like glands of the vulva and their disorders. Int J Gynecol Pathol Off J Int Soc Gynecol Pathol. 1994 Apr;13(2):150–60.
17. Higgins CM, Strutton GM. Papillary apocrine fibroadenoma of the vulva. J Cutan Pathol. 1997 Apr;24(4):256–60.
18. Konstantinova AM, Spagnolo DV, Stewart CJR, Kacerovska D, Shelekhova KV, Plaza JA, et al. Spectrum of Changes in Anogenital Mammary-like Glands in Primary Extramammary (Anogenital) Paget Disease and Their Possible Role in the Pathogenesis of the Disease. Am J Surg Pathol. 2017 Aug;41(8):1053–8.
19. Castro CY, Deavers M. Ductal carcinoma in-situ arising in mammary-like glands of the vulva. Int J Gynecol Pathol Off J Int Soc Gynecol Pathol. 2001 Jul;20(3):277–83.
20. Pelosi G, Martignoni G, Bonetti F. Intraductal carcinoma of mammary-type apocrine epithelium arising within a papillary hydradenoma of the vulva. Report of a case and review of the literature. Arch Pathol Lab Med. 1991 Dec;115(12):1249–54.
21. Obaidat NA, Awamleh AA, Ghazarian DM. Adenocarcinoma in situ arising in a tubulopapillary apocrine hidradenoma of the peri-anal region. Eur J Dermatol EJD. 2006 Oct;16(5):576–8.
22. Kazakov DV, Belousova IE, Sima R, Michal M. Mammary type tubulolobular carcinoma of the anogenital area: report of a case of a unique tumor presumably originating in anogenital mammarylike glands. Am J Surg Pathol. 2006 Sep;30(9):1193–6.
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Published
2018-02-23
How to Cite
Bianchi, A., Ochogavia-Seguí, A., Jimenez-Segovia, M., Fernandez-Isart, M., Pagan-Pomar, A., Martinez-Corcoles, J. A., … Gonzalez-Argente, X. (2018). BREAST TISSUE IN BENIGN TUMOR OF ANAL MARGIN. Annals of Mediterranean Surgery, 1(1), 13–16. Retrieved from https://edicions.uib.es/ojs/index.php/AMS/article/view/380
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